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KMID : 0370219760200020092
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Yakhak Hoeji
1976 Volume.20 No. 2 p.92 ~ p.96
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The Effect of Insulin on Lactate Dehydrogenase Isozyme in the Liver, Muscle and Serum of Albino Rats
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임중기/Lim CK
최기송/Choi KS
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Abstract
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A series of experimental groups has been studied in the state of hypoglycemia caused by a single intraperitoneal injection of insulin after 24 hrs of fasting albino rats and then the variation of LDH activities and LDH isozyme patterns in the liver, muscle and serum had been reported. The total LDH activity has been elevated in the liver and the muscle above the average level for control group, but increased continusly during 20 min and decreased in the 20~45 min intervals and increased again in 45 min in the serum. The change of LDH isozyme patterns had been shown that in the liver LDH5 was increased, LDH4 was decreased and in the muscle LDH1 was diminished by 30 min, was restored again after 45 min and LDH2 decreased about 94 percentage at 30 min, increased again to the average value and LDH5 increased to 30 min, decreased by 45 min and increased greater again after 45 min and in the muscle LDH3, LDH4 and LDH5 were increased to the greatest by 20 min, decreased in 20~45 min intervals and increased again after 45 min.
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